| 儿童泌尿系感染的临床特点、病原菌分布及耐药性分析 |
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| 引用本文： | 高晓洁,李永柏,赵维玲,杨军,马祖祥,王凯,张蕾.儿童泌尿系感染的临床特点、病原菌分布及耐药性分析[J].实用儿科临床杂志,2010(5). |
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| 作者姓名： | 高晓洁 李永柏 赵维玲 杨军 马祖祥 王凯 张蕾 |
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| 作者单位： | 深圳市儿童医院免疫肾脏病科; |
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| 摘 要： | 目的了解儿童泌尿系感染(UTI)的临床特点、常见病原菌分布及耐药现状,为临床用药提供依据。方法分析本院2000年1月-2007年2月住院的UTI患儿临床资料和尿培养结果,结合几种常见革兰阴性杆菌的药敏试验进行耐药性分析。结果本组确诊UTI的98例患儿中<1岁者29例(30%);无典型UTI阳性症状者19例(19.4%);泌尿系影像学检查异常者32例(32.7%);泌尿道畸形、输尿管狭窄或伴膀胱输尿管返流(VUR)者11例(11.2%)。尿标本共培养分离出病原菌105株,其中革兰阴性菌84株(80.0%),革兰阳性菌17株(16.2%),真菌4株(3.8%)。革兰阴性菌以大肠埃希菌、肺炎克雷伯杆菌、铜绿假单胞菌为主,革兰阳性菌以肠球菌和葡萄球菌为主。55株大肠埃希菌中分离出33株产超广谱β-内酰胺酶菌株(60%)。氨苄西林、头孢唑啉等对革兰阴性菌严重耐药,辅以酶抑制剂(如舒巴坦或甲巯咪唑)后耐药率明显降低;三代头孢菌素对铜绿假单胞菌敏感性良好,而对大肠埃希菌、肺炎克雷伯杆菌呈现中等耐药;亚胺培南、阿米卡星和环丙沙星耐药率最低。结论UTI患儿中小婴儿发病率较高,应高度警惕泌尿道畸形、输尿管狭窄或VUR等并发症的发...
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| 关 键 词： | 泌尿系感染 病原菌 耐药性 儿童 |
Evaluation of Clinical Features,Pathogen Distribution and Antimicrobial Resistance in Children with Urinary Tract Infection |
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| Abstract: | Objective To investigate the clinical features,pathogen distribution and antimicrobial resistance in children with urinary tract infection(UTI),and to search for a practical guidance of the clinical medication.Methods The clinical features,pathogen distribution and antimicrobial resistance in 98 cases of culture-positive hospitalized children with UTI from Jan.2001 to Feb.2007 were analyzed.Results Twenty-nine children out of 98 cases were younger than 1 year-old(30%),while 19 cases out of them showed atypi... |
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| Keywords: | urinary tract infection pathogen drug resistance child |
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