HRCT与PET/CT联合诊断孤立性肺结节

目的 探讨HRCT与PET/CT相结合诊断孤立性肺结节(SPN)的价值.方法 88例经病理或临床证实的SPN接受PET/CT显像和HRCT检查；PET/CT用目测法结合半定量法判断病灶的良恶性,HRCT根据病灶的形态学特征判断其良恶性；比较单纯HRCT、PET/CT和联合诊断对SPN的判断结果.结果 88例SPN中,44例良性,44例恶性.HRCT和PET/CT对恶性SPN内部和周围征象的检出率均高于良性SPN(P均＜0.05),联合诊断的特异度和准确率均高于单独HRCT和PET/CT(P均＜0.05).结论 HRCT与PET/CT联合诊断SPN的特异度和准确率均较单独诊断为高,值得临床推广.

HRCT combining with PET/CT in diagnosis of solitary pulmonary nodules

Objective: To explore the value of HRCT combining with PET/CT in diagnosing solitary pulmonary nodules (SPN). Methods: Eighty-eight patients of SPN confirmed by pathology or follow-up were examined with PET/CT and HRCT. Differential diagnosis of benign and malignant SPN were made using morphological characteristics on HRCT and visual method combined with semi-quantitative method on PET/CT. The results of simple HRCT, PET/CT and combining diagnosis were compared. Results: Forty-four SPN were malignant, and the other 44 were benign. The detection rates of internal and peripheral features of malignant SPN by using HRCT and PET/CT were higher than that of benign ones (all P<0.05). The specificity and accuracy rate of combining diagnosis were higher than those of individual HRCT and PET/CT (all P<0.05). Conclusion: HRCT combining with PET/CT has higher specificity and accuracy rate than single HRCT or PET, worthy to be popularized in clinical practice.