二维应变超声心动图及左房容积指数定量评价肥厚型心肌病患者左房功能

 目的探讨二维应变心动图及左房容积指数定量评价肥厚型心肌病（HCM）患者左房功能的价值。方法HCM患者37
例，测量左房被动射血分数、左房主动射血分数、左房容积指数、房间隔和左房侧壁二维应变，并与35 例正常人进行比较。结果
与正常对照者比较，HCM患者左房被动射血分数、主动射血分数和左房二维应变均显著降低（P < 0.05，P < 0.01，P < 0.05），左
房容积指数显著增高（P < 0.01）。HCM患者中左房容积指数与左房应变呈负相关（r =-0.73，P < 0.05）。结论HCM患者左房功
能减低，二维应变超声心动图及左房容积指数均能定量评价HCM患者的左房功能。

Quantitative Assessment of Left Atrial Function in Patients with Hypertrophic Cardiomyopathies Using Twodimensional Strain Echocardiography and Left Atrium Volume Index

Objective To evaluate the functions of the left atrium using two-dimensional strain（2DS）echocardiography and left atrium vol-
ume index（LAVI）in the patients with hypertrophic cardiomyopathy （HCM）and explore its clinical value. Methods There were 37 pa-
tients with HCM and 35 healthy subjects enrolled in our study. Left atrial passive ejection fraction （LAPEF）and left atrial active ejection
fraction （LAAEF）were calculated using Simpson’s method. The analysis for atrial longitudinal peak systolic strain （S），peak systolic stain
rate（SRs），peak early diastolic stain rate（SRe）and peak late diastolic strain rate（SRa）on the interatrial septum and the lateral wall of
the left atrium were performed using 2DS echocardiography. Results LAPEF and LAAEF significantly decreased compared with those in
the control group （ P < 0.05，P < 0.01）. LAVI in HCM group increased compared with that of the control group （ P < 0.01）. S，SRs，SRe
and SRa of the interatrial septum and the lateral wall were lower in patients with HCM than those in control group （ P < 0.05）. LAVI was
negatively correlated to 2DS （P =0.73，P < 0.05）. Conclusion The left atrial functions decreased in patients with HCM. 2DS and LAVI
are readily obtained parameters that provide unique data about global and segmental atrial functions.