前置胎盘与小于胎龄儿关系的临床研究

目的 研究前置胎盘及类型是否会影响新生儿体质量,增加小于胎龄儿(SGA)的发生率.方法 回顾性分析290例于2013年1月至2016年12月在该院产科住院的前置胎盘患者的临床资料;随机选择同期住院的290例非前置胎盘孕妇为对照组.采用x2检验、标准t检验比较分析前置胎盘及其类型对胎儿孕周、新生儿体质量、SAG的影响,并采用Logistic回归分析不同类型前置胎盘与不良妊娠结局的关系.结果 与非前置胎盘组相比,前置胎盘组患者年龄偏大[(30.9士4.6)岁vs.(29.1±4.0)岁,P＜0.01],孕次偏多[(3.2土1.8)次 vs.(2.2±1.4)次,P＜0.01],产次偏多[(1.4士0.7)次vs.(1.1±0.6)次,P＜0.01],产时孕周偏小[(37.7±1.7)周vs.(39.0士1.5)周,P＜0.01].完全性前置胎盘、凶险性前置胎盘新生儿体质量分别为(3 038.1±450.0)、(2 940.9±503.0)g,与非前置胎盘组相比,体质量均明显偏低(P＜0.05).经校正孕妇年龄、孕次、产次、妊娠期糖尿病(GDM)、胎龄等风险因素后,完全性前置胎盘、凶险性前置胎盘SGA发生风险稍偏高[(OR 1.21,95％CI(0.29,6.02);OR 2.25,95 ％CI(0.88,5.77)],但差异无统计学意义(P＞0.05).结论 完全性前置胎盘、凶险性前置胎盘SGA的发生风险偏高.

Clinical study on relation between placenta previa and small for gestational age

Objective To study whether placenta previa and type affect the body mass of newborns and increase the occurrence rate of small for gestational age (SGA).Methods The clinical data in 290 inpatients with placenta previa in our hospital from January 2013 to December 2016 were retrospectively analyzed;contemporaneous 290 inpatients with non-placenta previa were randomly selected as the control group.The influences of placenta previa and type on fetal gestational weeks,neonatal body mass and SGA were comparatively analyzed by using the standard t test or Chi-square tests.The Logistic regression analysis was adopted to analyze the association between placenta previa and the adverse pregnancy outcomes.Results Compared with non-placenta previa group,the age in the patients with placenta previa was elder(30.9 ±4.6 vs.29.1 ± 4.0,P＜0.01),had more gravidas (3.2 ± 1.8 vs.2.2±1.4,P＜0.01) and parities (1.4+0.7 vs.1.1±0.6,P＜0.01),lower pregnant weeks at birth (37.7±1.7 vs.39.0± 1.5,P＜0.01).The neonatal body masses in the complete placenta previa and dangerous placenta previa were (3 038.1 ± 450.0)g and (2 940.9 ± 503.0)g respectively,which were on the significantly lower side compared with the non-placenta previa group(P＜ 0.05).After correcting the risk factors of ages,gravidas,parities,GDM and gestation weeks,the risk of complete and dangerous placenta previa was slightly higher[OR 1.21,95％CI(0.29,6.02);OR 2.25,95％CI(0.88,5.77)],but the difference was not statistically significant.Conclusion Complete and dangerous placenta previa has a higher risk of SGA.