THT和BCG交替灌注防治膀胱癌术后复发

目的 观察噻替哌和卡介苗化学免疫预防膀胱癌术后复发的疗效。方法 对65例浅表性膀胱癌患术后应用噻替哌40mg和卡介苗60mg，每周1次进行交替膀胱灌注，共灌注12次，以后每间隔3个月灌注1次，持续2年。结果 随访2－9年，平均4．6年，肿瘤复发率为8．1％。结论 噻替哌和卡介苗交替膀胱灌注具有协同治疗,经只应用其中一种可明显减少膀胱癌术后复发率。

Intravesical Instillation with Thiotepaand Bacillus Calonette-Guerin to Prevent Postoperative Recurrence of Bladder Tumor

Objective To investigate the clinical effect of intravesical instillation with the Thiotepa and Bacillus Calmette-Guerin for the prevention of postoperative recurrence of bladder tumor.Methods 65 patients with superficial bladder cancer were included in this study.All patients received intravesical instillation of 20mg the Thiotepa or 60mg Bacillus Calmette-Guerin in turn once a week postoperatively for 12 weeks.Then intrvesical instillation was performed every 3 months for 2 years.Results All patients have been followed up for 2 to 9 years,with the average length of 4.6 years.The recurrence rate was 8.1%.Conclusion Intravesical instillation of the Thiotepa and Bacillus Calmette-Guerin in turn are effective to reduce the postoperative recurrence rate of bladder tumor.