替米沙坦联合卡维地洛治疗慢性充血性心力衰竭疗效观察

目的研究替米沙坦联合卡维地洛治疗慢性充血性心力衰竭的临床疗效。方法选择2010年12月～2013年12月来我院就诊的CHF患者80例。根据治疗方法不同分为观察组（替米沙坦联合卡维地洛治疗）和对照组（替米沙坦治疗），每组各40例，比较两组的疗效及两组患者治疗前后的左室收缩末内径（LVESd），左室舒张末内径（LVEDd），左室射血分数（LVEF）。结果观察组的总有效率达95．0％，对照组的总有效率为77．5％，观察组的疗效明显优于对照组（P〈0．05）。治疗后，观察组患者LVEDd、LVESd均较对照组显著降低，观察组患者LVEF均较对照组明显升高（P〈0．05）。结论替米沙坦联合卡维地洛治疗慢性充血性心力衰竭疗效确切，可以明显改善患者的心功能，值得推广和应用。

The clinical efficacy of telmisartan combined with carvedilol in treatment of chronic congestive heart failure

Objective To investigate the clinical efficacy of telmisartan combined with carvedilol in treatment of chronic congestive heart failure. Methods Selected 80 patients with CHF in our hospital from December 2010 to December 2013, were divided into two groups （telmisartan combined with carvedilol therapy） and control group （telmisartan） according to the different treatment methods,each group had 40 cases, the efficacy and LVESd, LVEDd,LVEF were compared before and after treatment between two groups. Results After treatment,the total effective rate of the observation group was 95.0%,the total effective rate of the control group was 77.5%,the efficacy of the observation group was significantly better than the control group （P 〈 0.05）.After treatment,the LVEDd,LVESd of the observation group were significantly lower than the control group,the LVEF of the observation group was significantly higher than the control group （P 〈 0.05）. Conclusion Telmisartan combined with carvedilol in treatment of chronic congestive heart failure have good efficacy,can significantly improve the heart function of CHF patients,should be promoted and applied.