原发性腹膜后肿瘤600例临床研究

[目的]总结原发性腹膜后肿瘤(PRPT)临床治疗经验,分析影响PRPT术后效果的因素。[方法]回顾性分析解放军总医院600例PRPT的临床资料。[结果]600例PRPT中546例行手术,病理结果恶性369例,良性177例。366例获随访,随访时间1个月～15年。PRPT完全切除者的1、3、5年生存率分别为:90.5%、73.2%、53.6%,恶性PRPT部分切除者的1、3、5年生存率分别为:70.6%、32.0%、5.7%(P<0.01)。Cox多因素回归分析显示:PRPT的局部复发、生存期与肿瘤是否完全切除、肿瘤大小、肿瘤细胞的分化程度明显相关。[结论]充分做好PRPT手术前准备,提高肿瘤完全切除率,是降低PRPT肿瘤复发,提高生存率的关键。

A Study of Primary Retroperitoneal Tumor in 600 Cases

To summarize the experience of management for primary retroperitoneal tumor(PRPT)and to analyze the factors influencing the effect after op-eration.The data of600cases with PRPT in General Hospital of PLA were reviewed retrospectively.Of600cases with PRPT,546cases were surgically treated.Among them,369malignant and177benign were proved.Three hundred and sixty-six cases were followed-up for1month to15years.The1-,3-,and5-year survival rates in complete resection patients were90.5%,73.2%,53.6%,respectively,and those in incomplete resection patients were70.6%,32.0%,5.7%,respectively(P<0.01).The Cox multi-various regression analysis showed that incomplete tumor resection,size of tumor and histological grade were associated with local recurrence and survival.[Conclusion]Sufficient pre-operative preparation,and complete tumor resection are important roles for reducing recurrence and improving survival.