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1例重型新型冠状病毒肺炎治愈患者的药物治疗分析
引用本文:郭鑫,曲若宁,郭义明.1例重型新型冠状病毒肺炎治愈患者的药物治疗分析[J].中国药业,2020(7):49-52.
作者姓名:郭鑫  曲若宁  郭义明
作者单位:吉林大学中日联谊医院药学部
摘    要:目的探讨重型新型冠状病毒肺炎(COVID-19)的临床特征,总结临床药物治疗经验。方法根据病历资料分析1例重型COVID-19患者的临床症状和药物治疗信息。结果该患者有明确的流行病学史,主要临床表现有发热、咳嗽、乏力等,指氧饱和度、电解质等实验室检查指标和胸部影像学异常,在无创呼吸机通气支持基础上,采用抗病毒、抗炎、改善呼吸功能等药物对症治疗后治愈出院。结论重型COVID-19临床表现复杂,病情进展快,可参照国家卫生健康委员会《新型冠状病毒肺炎诊疗方案》制订基本治疗措施,同时根据临床症状变化进行个体化药物对症治疗。

关 键 词:新型冠状病毒  新型冠状病毒肺炎  药物治疗  药物效应学  合理用药

Drug Therapy in a Cured Patient with Severe Coronavirus Disease 2019
GUO Xin,QU Ruoning,GUO Yiming.Drug Therapy in a Cured Patient with Severe Coronavirus Disease 2019[J].China Pharmaceuticals,2020(7):49-52.
Authors:GUO Xin  QU Ruoning  GUO Yiming
Institution:(Department of Pharmacy,China-Japan Union Hospital of Jilin University,Changchun,Jilin,China 130033)
Abstract:Objective To investigate the clinical characteristics of a patient with severe coronavirus disease 2019(COVID-19)and summarize the experience of clinical drug therapy.Methods The clinical symptoms and medication information of a patient with severe COVID-19 were analyzed according to his medical records.Results The patient had a clear epidemiological history,the main clinical symptoms were fever,cough,fatigue,etc.,and his laboratory examination indicators(such as blood oxygen saturation,electrolyte and so on)and chest imaging were abnormal.The patient was cured and discharged after drug symptomatic treatment with antiviral,anti-inflammatory,improvement of respiratory function on the basis of non-invasive ventilator ventilation support.Conclusion The clinical symptoms of the patient with severe COVID-19 are complex and the disease progress is rapid.The basic treatment plan can be made by referring to the Diagnosis and Treatment Plan for the COVID-19 released by the National Health Commission.Meanwhile,individualized drug therapy should be carried out for symptomatic treatment according to the changes in clinical symptoms.
Keywords:severe acute respiratory syndrome coronavirus 2  coronavirus disease 2019  drug therapy  pharmacodynamics  rational drug use
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