| 雷公藤内酯醇生物贴的稳定性研究 |
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| 引用本文： | 钱丽萍,阙慧卿,林绥,彭华毅,李晓慧,郭舜民. 雷公藤内酯醇生物贴的稳定性研究[J]. 医学教育探索, 2012, 35(3): 182-184 |
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| 作者姓名： | 钱丽萍 阙慧卿 林绥 彭华毅 李晓慧 郭舜民 |
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| 作者单位： | 1.福建省医学科学研究院，福建 福州 350001 2.福建省卫生技术学院，福建 福州 350001 |
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| 基金项目： | 福建省科技重大专项（2009YZ0001-1-3）；福建省医学创新项目（2009-CX-16）；福建省省属公益类科研院所基本科研专项（2011R1034-3） |
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| 摘 要： | 目的 研究雷公藤内酯醇生物贴中雷公藤内酯醇在不同条件下的稳定性。方法 通过影响因素试验、加速试验、长期留样试验，采用高效液相色谱法，测定雷公藤内酯醇，考察雷公藤内酯醇生物贴的稳定性。结果 经过光照、升温、加湿、加速等试验，雷公藤内酯醇生物贴中的雷公藤内酯醇的量变化不大。结论 雷公藤内酯醇生物贴在市售包装及贮藏条件下，质量稳定。
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| 关 键 词： | 雷公藤内酯醇生物贴；稳定性；高效液相色谱 |
Study on stability of Triplolide Biological Patches |
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| QIAN Li-ping,QUE Hui-qing,LIN Sui,PENG Hua-yi,LI Xiao-hui,GUO Shun-min. Study on stability of Triplolide Biological Patches[J]. Researches in Medical Education, 2012, 35(3): 182-184 |
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| Authors: | QIAN Li-ping QUE Hui-qing LIN Sui PENG Hua-yi LI Xiao-hui GUO Shun-min |
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| Affiliation: | 1.Fujian Medical Science Research Institute, Fuzhou 350001, China 2.Fujian School of Health Technology, Fuzhou 350001, China |
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| Abstract: | Objective To study the stability of Triplolide Biological Patches (LTBP). Methods Triplolide content was determinated by HPLC method through strengthen test, accelerated test, and long-term restained sample testing. And the stability of LTBP was investigated. Results Triptolide was relatively stable due to light, temperature, humidity, accelerated testing, and long-term testing. Conclusion The results show that LTBP could be relatively stable in the commercial packaging and storage condition in market. |
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| Keywords: | Triplolide Biological Patches (LTBP) stability HPLC |
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