Expression of genes in normal human monocytes in response to Aspergillus fumigatus. |
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| Authors: | Ernst K R?dland Morten Mattingsdal Ole K Olstad Reidun Ovsteb? Peter Kierulf Fredrik Muller Stig S Fr?land |
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| Affiliation: | Research Institute for Internal Medicine, Rikshospitalet-Radiumhospitalet Medical Center, Medical Department, Section of Clinical Immunology and Infectious Diseases, Oslo, Norway. kristian.rodland@rr-research.no |
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| Abstract: | The objective of these studies was to investigate genes of importance in the pathogenesis of Aspergillus infections. To do so, we employed microarray methodology to explore gene expression in human monocytes infected with Aspergillus conidia as compared with unstimulated monocytes and those stimulated with lipopolysaccharide (LPS) signaling through TOLL-like receptor 4 (TLR4). We found 997 (P
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