低频超声终止妊娠Ⅰ:胚胎宫内心电模型建立和分析

目的：建立胚胎宫内心电模型并进行分析。方法：采用引导兔胚胎宫内心电及直视下引导胚胎心电的方法，记录了妊娠１５天至２５天的４０只兔胚胎心电。结果：兔胚胎心电具有Ｐ波。ＱＲＳ波群。４０只胚胎宫内记录的心率为１８２．８±３０．６ｂｐｍ，Ｒ波电压幅度为３３１．５±１５０．６μｖ，剖开子宫保留胎盘血循环并保持羊膜完整，按头端负极、左腿为正极的二导联方式引出的胚胎心电频率为１８９．２±２０．７ｂｐｍ，Ｒ波电压幅度为２２０．６±６２．５μｖ。此外还分析了胚胎宫内心电的波型及出现频率。结论：该模型为兔胚胎的急性损伤监测提供了较好的生理指标。

Establishment and Analysis of ECG Model of Intrauterine Rabbit Embryos

Objective: To study the relationship of the expression of P glycoprotein (P gp) in hepatocellular carcinoma (HCC) to invasion and intrahepatic metastasis Methods: Surgical samples of 47 patients with HCC were investigated using immunohistochemical method in combination with computer imaging analytic technique Results: In HCC, anti P gp immunostaining was mainly localized in the cellular membrane A significantly higher positive percentage of P gp expression was observed in HCC tissues than normal liver tissues ( P <0 01) HCCs with intrahepatic metastasis had a significantly higher P gp expression level than those without intrahepatic metastasis ( P <0 01) The expression level of P gp in HCCs with invasion was significantly higher than that in HCCs without invasion ( P <0 05) Conclusion: P gp may play an important role in the invasion and intrahepatic metastasis of HCC P gp expression level in tumor correlates the progression of HCC