| 褶合曲线分析法同时测定安痛定片剂中的三组分的含量 |
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| 引用本文： | 丁立新,韩宁,高金波,张羽男. 褶合曲线分析法同时测定安痛定片剂中的三组分的含量[J]. 黑龙江医药科学, 2004, 27(5): 9-10 |
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| 作者姓名： | 丁立新 韩宁 高金波 张羽男 |
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| 作者单位： | 佳木斯大学化学与药学院,黑龙江,佳木斯,154007;佳木斯制药厂,黑龙江,佳木斯,154002 |
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| 摘 要： | 目的：不经分离同时测定安痛定片剂中三组分的含量。方法：以褶合光谱为基础，结合当前最优秀的数值计算法——偏最小二乘法(PLS法)利用计算机信息处理技术的褶合曲线分析法。结果：安痛定片剂中非那西丁、氨基比林和苯巴比妥三组分的平均回收率及相对标准偏差(RSD)分别为99．73％，0．84％；99．35％，0．73％；100．3％，1．85％。结论：该方法可以用于安痛定片剂质量的监控。
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| 关 键 词： | 褶合曲线分析法 安痛定 非那西丁 氨基比林 苯巴比妥 |
| 文章编号： | 1008-0104(2004)05-0009-02 |
Simultaneous determination of three components in the compound Antongding tablet with convolution curve analytical system |
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| DING Li-xin ,HAN Ning ,GAO Jin-bo ,ZANG Yu-nan. Simultaneous determination of three components in the compound Antongding tablet with convolution curve analytical system[J]. Heilongjiang Medicine and Pharmacy, 2004, 27(5): 9-10 |
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| Authors: | DING Li-xin HAN Ning GAO Jin-bo ZANG Yu-nan |
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| Affiliation: | DING Li-xin 1,HAN Ning 2,GAO Jin-bo 1,ZANG Yu-nan 1 |
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| Abstract: | Objective: To simultaneously determine three main components in the compound Antongding tablet without any separation. Methods: Based on convolution spectrometry together with the excellent caculation method-PLS method we used convolution spectrometry of computer information process technology. Results:The components of compound children's Phenobarbital tablet were Aspirin Phenacetin Caffine and Phenobarbital .Their average recycle rates and RSD are 99.73%,0.84%;99.35%,0.73%;100.3%,1.85%.Conclusion: The method is used for qualitative control of compound Antongding tablet. |
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| Keywords: | convolution curve analytical system Antongding tablet Phenacetin Caffine Phenobarbital |
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