胸腺肽治疗乙型肝炎的疗效对照观察

本文对乙型肝炎30例随机分为两组,观察组应用胸腺肽治疗20例,对照组应用健肝胶囊治疗10例,疗程6个月。结果:自觉症状与SGPT值较治疗前有改善,但与对照组比较无差异:特异性细胞免疫指标中灭活HBsAg疫苗皮试与对照组比较有显著差异,HBV各项血清学标记两组均无明显变化。表明胸腺肽作为免疫增强剂对乙型迁、慢性肝炎的治疗作用是有限的。治疗过程中无不良反应和副作用。

The effect of controlled treatment of chronic hepatitis B with Thymidine

Thirty cases of chronic hepatitis B were divided into two groups at random. Iwenty cases were treated with thymidine and 10 cases with capsules wholesome to liver. The course of treatment for both group was six months. The results were as follows. The self-feeling and ALT level of the patients in the thymidine group after treatment were apparently better than before treatment, but not significantly different from those in the control group. The specific cellular im munity indices, the results of skin test with inactivated HBsAg vaccine became improved in bothgroups after treatment, but the results in the thymidine group were significantly better than thosein the control group. The serelogical markers of HBV infection revealed no significant changes inboth groups. The results showed that thymidine, as an immunity-enhaucing drug, had no appa-rent therapeutic effect on chronic hepatitis B. There were no untoward reaction and side effectsin the course of treatment.