Morphologic changes of the liver following chemotherapy for metastatic breast carcinoma: CT findings |
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Authors: | A. Shirkhoda S. Baird |
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Affiliation: | (1) Department of Diagnostic Radiology, M.D. Anderson Cancer Center, 1515 Holcomb Boulevard, 77030 Houston, TX, USA;(2) Present address: Department of Diagnostic Radiology, William Beaumont Hospital, 3601 West 13 Mile Road, 48073 Royal Oak, MI, USA;(3) Present address: Department of Radiology, St. Lukes Episcopal Hospital, 77030 Houston, TX, USA |
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Abstract: | Thirty patients with metastatic breast carcinoma to the liver underwent systemic chemotherapy. Twentyfour of these patients also received hepatic arterial infusion chemotherapy, three in conjunction with hepatic artery embolization. The morphologic changes of the liver believed to be due to chemotoxic effect of treatment occurred in 27 patients, and were evaluated by serial computed tomography (CT) examinations. These included fatty changes in seven patients, severe cirrhotic changes in four, localized atrophy with regional contour changes in three, and areas of low density in the regions of previously treated metastases in 13. The CT features of cirrhosis included density changes along with nodular irregularity of the hepatic borders with marked decrease in liver size and development of ascites. |
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Keywords: | Abdomen, CT Liver, metastasis Chemotherapy, complications |
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