抗HIV的中药及其有效成分研究进展

通过国际网络、国内外文献资料查新等手段对最近6年来具有抗HIV活性的中药及其相关化合物进行综述。发现中药或天然药用植物中含有多种抗HIV的药理活性物质,如生物碱类、蛋白质类、黄酮类、槲皮素类、萜类、木质素类等。有望从中获得抗HIV的有效药物,并为实验室研究工作和临床用药做参考。因此从天然产物中寻找高效低毒的抗HIV药物为今后的重要研究方向。

Recent progress on anti-HIV research of traditional Chinese medicine and components

This paper summarized the recent 6 years' progress of anti-HIV compounds and traditional Chinese medicines by searching international network and reviewing the domestic and foreign literature.Traditional Chinese medicinal appeared to be a rich source of potentially useful materials for the treatment of human immunodeficiency virus infection.Some of them are much more potent in anti-HIV activity.And some components extracted from the herbs are even more tonic than the crude herb medicines.It has been proved that some active components such as alkaloids,proteins,flavonoids,quercetin,terpene,lignanoid are able to work on anti-HIV.People should pay more attention to the study of traditional Chinese medicine and the leading compounds on anti-HIV/AIDS in the clinic and in the laboratory.So searching for high efficacy and low toxicity anti-HIV drug from traditional Chinese medicine is an important and prospective research direction in the future.