高频超声检测2型糖尿病颈总动脉内中膜与体质量指数的关系

目的:探讨2型糖尿病(T2DM)体质量指数(BMI)与颈总动脉内中膜(IMT)及发生斑块的关系。方法:对90例35~79岁T2DM病人测量身高、体质量并计算BMI,按BMI值将研究对象分为正常体质量组、超质量组及肥胖组,对3组颈动脉进行检测,分析3组间BMI与颈总动脉IMT及斑块数量的关系。结果:T2DM病人IMT厚度随BMI增加而增加,两者呈中度正相关(r=0.49,P<0.05)。正常体质量组、超质量组及肥胖组3组间IMT及斑块数量有显著性差异,以肥胖组最高(P<0.05);颈总动脉IMT厚度及斑块数量随BMI增加而增加;3组间有显著性差异,肥胖组最高(P<0.05)。结论:T2DM病人BMI与IMT呈中度正相关,随BMI的增加,颈动脉粥样硬化及斑块的发生增加,BMI是T2DM患者发生动脉粥样硬化的独立危险因素。

The relationship between BMI and carotid artery IMT in type 2 diabetes mellitus

Objective: To study the relationship between BMI and carotid artery intima-media thickness(IMT) in type 2 diabetes mellitus(T2DM).Methods: BMI of 90 T2DM patients aged from 35 to 79 was calculated,the carotid artery was also detected by 2-dimensional and color doppler ultrasound.According to BMI,they were divided into three group: normals,overweigh and obesity.Results: Relationship between BMI and IMT was positive correlative.IMT was significantly different within the three groups(P<0.05).Compared with the BMI normal group,overweight and obesity’s IMT had significant difference(P<0.05) and it was highest in obesity’s.The incidence of carotid artery atherosclerotic plaque was also higher(P<0.05) .The highest was also in the obesity’s group.Conclusion: The IMT of carotid artery has positive correlative to BMI in patient with T2DM.The incidence of carotid artery atherosclerotic plaque is higher in the overweight and obesity groups.