| 中药治疗抑郁症的作用机制研究进展 |
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| 引用本文： | 毛庆秋,黄真. 中药治疗抑郁症的作用机制研究进展[J]. 中国中药杂志, 2007, 32(10): 877-880 |
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| 作者姓名： | 毛庆秋 黄真 |
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| 作者单位： | 浙江中医药大学,药学院,浙江,杭州,310053 |
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| 基金项目： | 浙江省自然科学基金;浙江省科技计划;浙江省教育厅资助项目 |
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| 摘 要： | 通过查阅国内外近年来有关药理研究文献并结合作者的相关研究成果,对中药治疗抑郁症的作用机制研究进展进行综述。研究证明,中药可以通过影响单胺类神经递质、兴奋性氨基酸毒性、下丘脑-垂体-肾上腺(HPA)轴、海马神经元及神经营养因子等因素起到治疗抑郁症作用,提示中药治疗抑郁症的作用是通过多途径、多靶点、多层次来实现的。
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| 关 键 词： | 中药 抑郁症 作用机制 |
| 文章编号： | 1001-5302（2007）10-0877-04 |
| 收稿时间： | 2006-10-11 |
| 修稿时间： | 2006-10-11 |
Research progress on therapeutic mechanism of depression treated by traditional Chinese medicine |
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| MAO Qing-qiu; HUANG Zhen. Research progress on therapeutic mechanism of depression treated by traditional Chinese medicine[J]. China Journal of Chinese Materia Medica, 2007, 32(10): 877-880 |
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| Authors: | MAO Qing-qiu HUANG Zhen |
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| Affiliation: | Department of pharmacy, Zhejiang University of Traditional Chinese Medicine, Hangzhou 31005, China |
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| Abstract: | To review the reports concering the mechanisms of traditional Chinese medicine in treating depression in recent years and combine research achievements of the authors, we summarized the research progress on therapeutic mechanism of depression treated by traditional Chinese medicine. Previous researches proved that traditional Chinese medicine played antidepressant role by affecting the monoamine neurotransmitters, excitotoxicity, Hypothalamus-Pituitary-Adrenal axis, hippocampal neurons and neurotrophic factor et al. It has suggested that depression treated by traditional Chinese medicine is through a lot of channels, target spots and levels. |
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| Keywords: | traditional Chinese medicine depression therapeutic mechanism |
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