输液不良反应的分析

目的：探讨输液不良反应（ADR）的一般规律及特点,指导临床合理用药。方法：对中国药学文摘（CPA）报道的148例输液ADR进行统计分析。结果：输液所致ADR在高年龄组发生率较高,多在用药半小时内发生。ADR累及机体多个器官系统,临床表现复杂多样,主要表现为变态反应,严重者可致过敏性休克甚至死亡。结论：应加强输液的应用监测,以减少严重ADR的发生。

Analysis of acid adverse drug reaction caused by infusion

Objective：To study the general pattern and characteristics of acid adverse drug reaction （ADR） caused by infusion to guide rational drug use.Methods：An analysis was conducted on 148 cases of ADR caused by infusion in CPA.Results：ADR caused by infusion often occurred in old aged group.The onset of ADR was usually within 30 min after infusion.ADR could involve in multiple organs and systems,and clinical manifestations were various,mainly were allergic reaction.Severe allergic reaction could result in anaphylactic shock and even death.Conclusion：The application monitor of infusion should be strengthened to reduce the occurrence of serious ADR.