有氧耐力训练对老年慢性阻塞性肺疾病患者免疫功能的影响

目的探讨有氧耐力训练对老年慢性阻塞性肺疾病患者免疫功能的影响。方法将68例中、重度COPD患者分为观察组38例及对照组30例，对照组给予COPD规范药物治疗，观察组在此基础上接受为期4周的有氧耐力训练，比较实验前后两组患者免疫功能情况。结果治疗前两组患者各项免疫指标比较，差异均无统计学意义（P〉0．05）；治疗后观察组CD3＋％、（CD3＋CD4＋）％、Th／Ts、（CD3＋CD19＋）％、（CD3＋-CD16＋＋CD56＋）％免疫指标值分别为（61．5±5．4），（36．2±9．8），（1．9±0．7），（12．8±4．6），（25．6±5．3）％，均高于对照组的（54．5±5．9），（29．9±8．9），（1．3±0．6），（10．6±3．2），（22．3±2．9）％，观察组（CD3＋＋CD8＋）％免疫指标值为（21．6±9．7）％，低于对照组的（27．6±11．7）％，差异均有统计学意义（t分别为5．008，2．773，3．946，2．342，3．269，-2．283；P〈0．05）。结论有氧耐力训练在老年COPD患者提高免疫功能方面具有积极的作用。

Influence of aerobic stamina exercises on immune function of elderly patients with chronic obstructive pulmonary disease

Objective To analyze the influence of aerobic stamina exercises on immune function of elderly patients with chronic obstructive pulmonary disease. Methods 68 cases of elderly patients with chronic obstructive pulmonary disease were divided into two groups, the experimental group （38 cases） and the control group （30 cases）. The control group received COPD standard medication while the experimental group received aerobic stamina sports for 4 weeks in addition. Two groups＇ immune function were compared before and after the treatment. Results No significant differences were observed between the two groups before any intervention was taken （P 〉 0.05 ）. The lever of CD3 ＋ %, （ CD3 ＋ ＋ CIM ＋ ） %, Th/Ts, （CD3 ＋ - CD19 ＋ ） %, （ CD3 ＋ - CD16 ＋ ＋ CD56＋ ）% （61.5 ＋5.4）, （36.2 ＋9.8）, （ 1.9 ±0.7）, （ 12.8 ±4.6）, （25.6 ±5.3）% ] were significantly higher in experimental group than in control group （ 54.5 ± 5.9）, （ 29.9 ± 8.9）, （ 1.3 ± 0.6）, （ 10.6 ± 3.2）, （22.3 ± 2.9 ） % ] after 6 weeks treatment. And the lever of （ CD3 ＋ ＋ CD8 ＋ ） % in experimental group （21.6 ± 9.7 ） % was significantly lower than that in control group （ 27.6 ± 11.7 ） % after 6 weeks treatment （ t = 5. 008,2. 773,3. 946,2. 342,3. 269, - 2. 283, respectively; P 〈 0.05 ）. Conclusions Aerobic stamina exercise has a positive effect on immune funetion of elderly patients with ehronic obstruetive pulmonary disease.