101例药品不良反应报告分析

目的:了解某院2011年度药品不良反应(adverse drug reaction,ADR)发生的规律和特点。方法:对大同市第四人民医院药剂科上报的101例药品不良反应报告进行统计分析。结果:101例药品不良反应注射给药占96.04%,一般的不良反应占95.05%,60岁以上的患者占17.80%,累及的器官/系统损害以皮肤及其附件为主占43.56%。药品主要以抗感染药物为主占所发生不良反应例数的31.68%,占药品品种数的32.56%。结论:医护人员应加强合理用药意识,注重临床用药监测,不断总结经验,确保患者用药的安全、有效,尽量避免不良反应的发生。

Analysis of 101 Adverse Drug Reaction Cases

Objective： To investgate the feature and regularity of the adverse drug reaction （ADR） occurring in the hospital in 2011. Method： 101 ADR cases collected in the hospital in 2011 were statistically analysed. Result： A- mong the 101 cases, the ADR induced by intravenous administration were primacy with 96.04%, followed by those in- duced by nomoral ADR with 95.05%. The female showed higher proportion than the male, and the senile patients aged 〉 60 accounted for about 17.08%. Lesions of skin and its appendages were accounting for 43.56%. The ADR in- duced by antimicrobial agents were primacy with 31.68%, which induced by the types of drugs were 32.56%. Conclu- sion： Medicial staff should enhance awareness of rationgal drug use, improve and strengthen the ADR monitoring, con- stantly sum up experience, to ensure patients safely and effectively as a result of keeping away from the occurrence of ad- verse reactions.