| 肿瘤微环境中的非肿瘤细胞 |
| |
| 引用本文： | 李璘,邱蓉丽,乐巍,姚卫峰,余果.肿瘤微环境中的非肿瘤细胞[J].中国药理学通报,2012,28(4):455-457. |
| |
| 作者姓名： | 李璘 邱蓉丽 乐巍 姚卫峰 余果 |
| |
| 作者单位： | 1. 南京中医药大学科技处,江苏南京,210046
2. 南京中医药大学药学处,江苏南京,210046 |
| |
| 基金项目： | 国家自然科学基金资助项目(No 81001599);江苏省高校自然科学基金资助项目(No 04KJB360100);江苏省中医药管理局基金资助项目(No LB09013);南京中医药大学国家基金预研基金资助项目(No XYY06) |
| |
| 摘 要： | 肿瘤微环境是影响肿瘤发展恶化的重要因素,其中的非肿瘤细胞对于肿瘤细胞及微环境的形成和改变具有决定性作用。该文从肿瘤微环境的组成及其功能特点和影响肿瘤微环境关系密切的非肿瘤细胞入手,较全面的阐述了非肿瘤细胞在肿瘤微环境形成过程中的功能作用及影响。
|
| 关 键 词： | 肿瘤 微环境 非肿瘤细胞 巨噬细胞 成纤维细胞 淋巴细胞 |
Non-tumor cells in tumor microenvironment |
| |
| LI Lin
,
OIU Rong-li
,
YUE Wei
,
YAO Wei-feng
,
YU Guo.Non-tumor cells in tumor microenvironment[J].Chinese Pharmacological Bulletin,2012,28(4):455-457. |
| |
| Authors: | LI Lin OIU Rong-li YUE Wei YAO Wei-feng YU Guo |
| |
| Institution: | 1(1.Dept of Science and Technology,2.School of Pharmacy,Nanjing University of Chinese Medicine,Nanjing 210046,China) |
| |
| Abstract: | Tumor microenvironment is a spatial structure including many kinds of cells and stroma around them,which interact each other to form a variety of crosstalks.Current research confirms that tumor progress and metastasis are involved in autocrine and paracrine by peritumor cells,which create a robust system that can regulate their response to treatment.Non-tumor cells in tumor environment play a crucial role.Proposed here is the therapy for cancer treatment,which could be more effective in destruction of the tumor microenvironment than just killing the tumor cells. |
| |
| Keywords: | tumor microenvironment non-tumor cells macrophage fibroflast cells lymphocyte |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
|
