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经心外膜点状射频消融犬心房颤动的研究
引用本文:郑衍平,冯金芝,王东明,李玉光. 经心外膜点状射频消融犬心房颤动的研究[J]. 解放军医学杂志, 2001, 26(11): 816-817
作者姓名:郑衍平  冯金芝  王东明  李玉光
作者单位:汕头大学医学院第一附属医院,
基金项目:广东省科委重点资助课题 (编号 19980 38)
摘    要:为探索心房颤动的点状消融途径,选用健康犬以电刺激结合乙酰甲胆碱滴注的方法制成颤模型,以自制4对双极电极进行心外膜电生理标测,于心房易损性最大的部位进行射频消融治疗。结果表明,10只犬成功达到消融终点,与消融前相比,窦性心率、P波时限、校正窦房结恢复时间及房内传导时间变化均无显著性差异。提示阵发性房颤可通过点状消融得到消除,房颤的发生机制可能与激发活动有关。

关 键 词:心房颤动 射频导管消融术 犬 电刺激 乙酰甲胆碱
修稿时间:2001-06-14

DISCRETE RADIOFREQUENCY CATHETER ABLATION FOR PAROXYSMAL ATRIAL FIBRILLATION IN A DOG MODEL
Zheng Yanping,Feng Jinzhi,Wang Dongming et al. DISCRETE RADIOFREQUENCY CATHETER ABLATION FOR PAROXYSMAL ATRIAL FIBRILLATION IN A DOG MODEL[J]. Medical Journal of Chinese People's Liberation Army, 2001, 26(11): 816-817
Authors:Zheng Yanping  Feng Jinzhi  Wang Dongming et al
Affiliation:Zheng Yanping,Feng Jinzhi,Wang Dongming et al . The First Affiliated Hospital of Shantou University Medical College,Shantou 515041
Abstract:To investigate an approach of treatment for atrial fibrillation with discrete ablation lesion, 12 dogs with experimental atrial fibrillation underwent radiofrequency catheter ablation. Atrial lesion was made at the most vulnerable site. The results showed that in 10 of 12 dogs persistent fibrillation could be ablated. There was no significant change in sinus heart rate, P wave duration, and corrected sinoatrial node recovery time (cSNRT). The results suggested that paroxysmal atrial fibrillation could be eliminated by point ablation of the lesion, and that trigger activity might be involved in the mechanism of atrial fibrillation.
Keywords:atrial fibrillation  catheter ablation  radiofrequency  dogs
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