结直肠癌肝转移的临床病理学特点分析

目的：探讨结直肠癌肝转移的临床及病理学特点，以期提高疗效。方法：对１９９４年４月～２０００年１１月入院的５５例结直肠癌同时伴肝转移病例与同期１００例结直肠癌无肝转移病例进行对比分析。结果：结直肠癌肝转移与肿瘤大小、大体类型、侵犯肠管周径、肠壁浸润深度、分化程度与淋巴结转移的病理因素有关。结论：本文提示原发癌肿直径大于３ｃｍ、大体病理为浸润型、侵犯肠管周径＞１／２圈、癌肿浸润浆膜或浆膜外、分化程度差及有淋巴结转移的病例易发生肝转移，因而对有上述情况的病例术中应仔细探查肝脏，术后加强随访，以提高肝转移的早期诊断。

Clinical and Pathological Characteristics of Colorectal Carcinoma with Liver Metastasis.

Objectives: To investigate the clinical and pathological characteristics of colorectal carcinoma with liver metastasis. Methods: Retrospective analysis was carried out in two groups of patients suffering from colorectal carcinoma with(n=55) and without(n=100) liver metastasis, admitted during the period from April 1994 through November 2000. Results: Liver metastasis happended more frequently in cases with diameter over 3cm and having infiltrated>1/2 of the intestinal circumsference, belonging to the invasive type, having positive lymph node(LN). Conclusions: Liver metastasis of colorectal carcinoma is related to the pathological type, the diameter and the depth of invasion of the primary lesion, as well as to the status of LN metastasis. Meticulous peroperative exploration and careful post-operative follow-up are mandatory in these patients.