不孕不育家庭男方精液质量调查分析

目的观察分析不孕不育家庭男方精液检查结果,了解长沙地区不孕不育家庭男方精液质量状况。方法选取2015年1月至2018年12月长沙市妇幼保健院爱心助孕义诊下乡活动中不孕不育家庭前来就诊的182例男性作为不育组,选取同期在该院行体外受精-胚胎移植术(IVF)的445例男性作为IVF组,另选取同期孕前检查结果均正常已正常生育的272例男性作为正常组,统计分析各组精液参数。结果 3组间进行两两比较,不育组年龄、精液pH值、精液液化时间、精子浓度、精子总数、精子总活力、精子前向运动百分率和精子畸形率与IVF组结果相近,差异均无统计学意义(P>0.05);不育组精液量低于IVF组,差异有统计学意义(P<0.05);不育组精液量、精子浓度、精子总数、精子总活力和精子前向运动百分率均低于正常组,精子畸形率高于正常组,差异均有统计学意义(P<0.05);正常组精液量、精子浓度、精子总数、精子总活力和精子前向运动百分率均明显高于IVF组,差异均有统计学意义(P<0.05)。结论不育组男性年龄和精液参数与IVF组相近,且两组年龄均大于正常组,两组精液参数明显劣于正常组,精子质量异常是不孕不育家庭男性不育的主要原因。

Investigation and analysis of semen quality in male of infertility family

Objective To observe and analyze the results of semen examination in infertile families and to understand the quality of semen in infertile families in Changsha.Methods A total of 182 males who were assisted by the infertility family in the rural areas from the Changsha Maternal and Child Health Hospital from January 2015 to February 2018 were selected as the infertility group.And 445 males received in vitro fertilization(IVF)were selected as IVF group.In addition,272 males of normal fertility before pregnancy were selected as normal group.The semen parameters of each group were statistically analyzed in our hospital.Results Pairwise comparison between the three groups showed that the age,pH value,liquefaction time,sperm concentration,total number,total vitality,percentage of forward motion and deformity rate of the infertile group were similar to those of the IVF group,the differences were not statistically significant(P>0.05).The amount of semen in the infertile group was lower than in the IVF group,the difference was statistically significant(P<0.05).The amount of sperm,concentration of sperm,total sperm,total sperm motility,and percentage of forward sperm movement in the infertile group were significantly lower than those in the normal group,sperm deformity rate is higher than normal group.The amount of semen,sperm concentration,total number,total vigor,percentage of forward motion and deformity rate in the normal group were significantly better than those in the IVF group,and the differences were statistically significant(P<0.05).Conclusion The age and semen parameters of males in infertile group are similar to those in IVF group,and the ages of both groups are higher than that of the normal group.The semen parameters of the two groups are obviously inferior to those of normal birth group.The abnormal sperm quality is the main reason for male infertility in infertile families.