新型冠状病毒肺炎疫情下重庆市医疗机构临床实验室生物安全现状调查

目的了解新型冠状病毒肺炎疫情下重庆市医疗机构临床实验室生物安全现状。方法于2020年2月8-15日,对重庆市42家新型冠状病毒肺炎定点救治医院临床实验室发放问卷调查,调查内容包括实验室基本情况、实验室生物安全设施设备配置、实验室个人防护用品配置、实验室未开展新型冠状病毒核酸检测原因、实验室生物安全培训情况等。结果在规定时间内收到26家实验室有效回报,26家定点医疗机构中二级和三级医疗机构各占50.0%。所有实验室均为已备案的生物安全二级实验室;无门禁装置实验室1家(3.8%),无自动可关闭门实验室2家(7.7%),无负压条件实验室22家(84.6%);自然通风实验室15家(57.7%);4家(13.4%)实验室安全设备未年检;6家(23.1%)实验室没有防护服储备。10家未开展新型冠状病毒核酸检测的实验室中有7家(70.0%)原因为三级生物安全防护用品缺乏。26家实验室均及时组织了人员培训,1家(3.8%)实验室组织了针对性的操作演练。结论实验室应加强安全设施设备的投入和监管,加大应急防护物资的储备,建立健全有效的生物安全培训体系,进一步提高临床验室应对新发、突发传染病的生物安全管理能力。

Survey of the laboratory biosafety in Chongqing medical institution under Coronavirus Disease 2019 pandemic

Objective To understand the biosafety status of clinical laboratories in Chongqing medical institutions under the Coronavirus Disease 2019(COVID-19)pandemic.Methods A questionnaire survey was conducted in clinical laboratories of 42 hospitals designated for the treatment of pneumonitis infected with COVID-19 in Chongqing from February 8,2020 to February 15,2020.The survey included basic laboratory conditions,laboratory biosafety facility equipment configuration,laboratory personal protective equipment configuration,and reasons of not detecting of Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2)nucleic acid,laboratory biosafety training,etc.Results A total of 26 laboratories reported valid results within the specified time.The 26 designated medical institutions accounted for 50.0% each of the secondary and tertiary medical institutions.All the laboratories were registered Biosafety Level 2,1 laboratory(3.8%)without access control devices,2 laboratories(7.7%)with automatic closing doors,22 laboratories(84.6%)with negative pressure conditions,15 laboratories(57.7%)with natural ventilation;4 laboratories(13.4%)without annual inspection of safety equipment;6 laboratories(23.1%)had not protective clothing.Seven(70.0%)of the 10 laboratories did not carry out the SARS-CoV-2 nucleic acid test were due to the lack of third-level biosafety protection supplies.A total of 26 laboratories had timely organized staff training,and 1 laboratory(3.8%)organized targeted operation walkthrough.Conclusion The laboratory should strengthen the investment and supervision of safety facilities and equipment,increase the reserve of emergency protective materials,and establish a sound and effective biosafety training system,so as to improve the laboratory′s biosafety management capabilities to respond to emerging infectious diseases.