普洱地区13774例育龄女性TORCH筛查及IgG抗体亲和力检查结果分析

目的探讨普洱地区育龄女性TORCH感染情况及流行特点,为该地区育龄女性孕期保健提供一定的参考依据。方法收集2017年3月至2019年3月来该院进行TORCH检查的育龄女性13774例,通过磁微粒发光化学免疫分析法定量检测TORCH特异性IgG和IgM抗体,依据检测结果,按受检女性的年龄段和不同季节分别统计弓形虫(TOX)、风疹病毒(RV)、巨细胞病毒(CMV)、单纯疱疹病毒(HSV)-Ⅰ、HSV-Ⅱ的IgG和IgM抗体阳性情况。分析IgG抗体亲和力结果。结果(1)TORCH-IgG抗体检测结果中,CMV-IgG抗体阳性率最高,为92.62%,TOX-IgG抗体阳性率最低,为6.33%;TORCH-IgM抗体检测结果中,CMV-IgM抗体阳性率最高,为0.86%,TOX-IgM抗体阳性率最低,为0.30%。(2)成年人TORCH-IgG抗体(除TOX)和TORCH-IgM抗体阳性率均高于未成年人(P<0.05)。(3)不同季节TORCH-IgM抗体阳性构成比差异均无统计学意义(P>0.05)。(4)TORCH-IgG抗体亲和力检测结果以高亲和力为主。结论育龄女性常规进行TORCH筛查及IgG抗体亲和力的检查,一方面可有针对性地预防TORCH感染,另一方面可为临床鉴别TORCH急性感染提供诊断依据。

Analysis of results of TORCH screening and IgG antibody affinity test among 13774 childbearing age females in Pu'er area

Objective To investigate and discuss the infection status and epidemic characteristics of TORCH among the childbearing age females in Pu'er area to provide a certain reference for the pregnant health care in the childbearing age females in this area.Methods A total of 13774 childbearing age females conducting the TORCH screening in this hospital from March 2017 to March 2019 were collected.The levels of TORCH specific IgG and IgM antibodies were detected by using the magnetic particles chemiluminescence immunoassay.According to the detection results,the IgG and IgM antibody positive results and IgG affinity of toxoplasma(TOX),rubella viruses(RV),cytomegalovirus(CMV),type Ⅰ and Ⅱ of herpes simplex virus were statistically analyzed by the age periods and different seasons.The result of IgG antibody affinity was analyzed.Results(1)In the TORCH-IgG antibodies detections,the positive rate of CMV-IgG antibody was the highest(92.62%),which of TOX-IgG antibody was the lowest(6.33%);in the various CMV-IgM antibodies detections,the positive rate of CMV-IgM antibody was the highest(0.86%),and which of TOX-IgM was the lowest(0.30%).(2)The positive rates of TORCH IgG(except for TOX)and TORCH IgM antibodies in adults all were higher than those in juveniles(P<0.05).(3)There was no statistically significant difference in the positive constituent ratio of TORCH-IgM antibody infection among different seasons(P>0.05).(4)The TORCH-IgG antibody affinity detection results were dominated by high affinity.Conclusion Routinely conducting the TORCH screening and IgG antibody affinity test for childbearing age females can not only targetedly prevent the TORCH infection,but also provide the diagnostic basis for clinical identification of TORCH acute infection.