Evaluation of the renal scanning agent N-succinyldesferrioxamine B in dogs |
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| Authors: | J D M Herscheid H Isaacs R B J de Jong A Hoekstra |
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| Institution: | (1) Radionuclide Centre, Free University, P.O. Box 7161, 1007 MC Amsterdam, The Netherlands;(2) Mallinckrodt Diagnostica (Holland) B.V., Westerduinweg 3, 1755 LE Petten, The Netherlands |
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| Abstract: | The mechanism of the excretion of 67Ga-N-succinyldesferrioxamine B (SDF) was investigated in five healthy dogs. Comparison of the SDF clearance rates for whole blood and plasma as well as SDF renograms with those of 131I-o-iodohippuric acid (OIH) and 111In-diethy-lenetriamine-pentaacetic acid (DTPA) revealed that SDF is cleared by glomerular filtration and not by an active tubular transport mechanism. |
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| Keywords: | Renography N-Succinyldesferrioxamine B |
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