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21例布洛芬缓释胶囊致不良反应文献分析
引用本文:杜佳新,顾玉红. 21例布洛芬缓释胶囊致不良反应文献分析[J]. 中国药房, 2007, 18(20): 1580-1582
作者姓名:杜佳新  顾玉红
作者单位:1. 哈尔滨医科大学附属第一临床医学院,哈尔滨市,150001
2. 哈尔滨医科大学附属肿瘤医院,哈尔滨市,150081
摘    要:目的:探讨布洛芬缓释胶囊致不良反应的特点及一般规律。方法:检索1996~2005年国内医药期刊报道的布洛芬缓释胶囊致不良反应案例,并进行统计、分析。结果:布洛芬缓释胶囊所致不良反应包括消化道出血、双下肢水肿、多脏器功能衰竭等,其在高年龄组发生率较高。结论:临床上应重视布洛芬缓释胶囊所致的不良反应,坚持合理用药。

关 键 词:布洛芬缓释胶囊  不良反应  文献分析
文章编号:1001-0408(2007)20-1580-03
收稿时间:2007-02-08
修稿时间:2007-02-082007-05-11

Adverse Drug Reactions Induced by Ibuprofen Sustained Release Capsules: Literature Analysis on 21 Cases
DU Jiaxin,GU Yuhong. Adverse Drug Reactions Induced by Ibuprofen Sustained Release Capsules: Literature Analysis on 21 Cases[J]. China Pharmacy, 2007, 18(20): 1580-1582
Authors:DU Jiaxin  GU Yuhong
Affiliation:1.The First Affiliated Clinical College Hospital of Harbin Medical Univesity,Harbin 150001, China;2.The Affiliated Tumor Hospital of Harbin Medical University,Harbin 150081, China
Abstract:OBJECTIVE:To study the characteristics and the general pattern of the ADR induced by ibuprofen sustained release capsule.METHODS:The ADR induced by ibuprofen sustained release capsule reported in domestic medical journals during 1996~2005 were collected and analyzed.RESULTS:ADR associated with ibuprofen sustained release capsule included alimentary tract hemorrhage,edema of both lower extremities,multi-organ functional failure,with advanced age group showing the highest incidence rate.CONCLUSION:Ibuprofen sustained release capsules should be used rationally with caution in case of ADR.
Keywords:Ibuprofen sustained release capsules  ADR  Literature analysis
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