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奥美拉唑或(和)庆大霉素治疗幽门螺旋杆菌十二指肠溃疡84例
引用本文:陈中和. 奥美拉唑或(和)庆大霉素治疗幽门螺旋杆菌十二指肠溃疡84例[J]. 中国新药与临床杂志, 1994, 0(1)
作者姓名:陈中和
作者单位:广东省四会县人民医院内科
摘    要:经内窥镜诊断幽门螺旋杆菌(HP)十二指肠溃疡,用奥美拉唑(Ome)20mg,qd或(和)庆大霉素(Gen)4万U,tid,po,治疗2wk。25例用Ome,23例用Gen,36例用Ome+Gen。在疗程末(3d内)和14d复查愈会率:Ome组72%和88%,Gen组61%和78%,Ome+Gen组92%和100%。4wkHP清除率则分别为52%,65%及83%。未见不良反应,可首选联合用药。

关 键 词:奥美拉唑;庆大霉素;幽门螺旋杆菌;十二指肠溃疡;联合药物疗法

Omeprazole or/and gentamicin in treating 84 patients with Helicobacter pylori duodenal ulcer
CHEN Zhong-He. Omeprazole or/and gentamicin in treating 84 patients with Helicobacter pylori duodenal ulcer[J]. Chinese Journal of New Drugs and Clinical Remedies, 1994, 0(1)
Authors:CHEN Zhong-He
Abstract:Helicobacter pylori(HP)duodenal ulcer diagnosed by endoscopy was treated with omeprazole 20 mg,qd(Ome),or/and gentamicin 40 000 units,tid,(Gen)po for 2 wk:Ome in 25 patients,Gen in 23 patients,and Ome Gen in 36 patients.Endoscopic and bacterial examinations were made right after(within 3 d)and 14 d after the end of the therapy course to check the healing rates:72% and 88% in Ome group,61% and 78% in Gen group, and 92% and 100% in Ome Gen group, respectively.The HP clearance rates were 52%, 65% and 83% respectively.No adverse effects were found.It is concluded that the combination drug therapy is the best choice.
Keywords:omeprazole  gentamicins  Helicobacter pylori  duodenal ulcer  combination drug therapy  
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