乌司他丁联合大黄治疗重症胰腺炎疗效观察

目的:探讨乌司他丁联合大黄治疗重症急性胰腺炎的疗效。方法:将56例重症急性胰腺炎患者随机分为治疗组和对照组:治疗组28例,应用乌司他丁联合大黄治疗;对照组28例,应用乌司他丁治疗。观察患者治疗前后血淀粉酶、血糖、血钙、白细胞计数,治疗后腹痛和腹胀缓解的时间,首次排便的时间,并发症发生率及平均住院天数。结果:治疗组腹痛和腹胀缓解时间短,并发症发生率低、平均住院天数短、实验室指标改善快。结论:乌司他丁联合大黄治疗重症急性胰腺炎可提高疗效。

The Combination of Ulinastatin and Rhubarb as an Effective Treatment for Severe Acute Pancreatitis

Objective: To determine the effectiveness of the combination of ulinastatin and rhubarb to treat severe acute pancreatitis(SAP).Method: 56 SAP patients were divided into treatment group and control group randomly and equally.The former group was treated with the combination of ulinastatin and rhubarb,while the latter one was cured with ulinastatin only.Serum amylase,glucose,calcium and white blood cell count were observed before and after the treatment.At the same time,the time of the alleviation of abdominal pain and distension,the first defecation as well as the complication rate and the average duration of hospitalization were observed after the treatment.Result: The patients in the treatment group experienced alleviation of abdominal pain and distension earlier with lower complication rate and shorter duration of hospitalization than the patients in the control group.Meanwhile,the patients,laboratory tests in the treatment group returned to normal levels faster than those in control group.Conclusion: The combination of ulinastatin and rhubarb was effective to treat severe acute pancreatitis.