择期经皮冠状动脉介入治疗对心肌梗死患者左室重构的影响

目的 :应用二维超声心动图对接受经皮冠状动脉介入治疗的心肌梗死患者术前、术后 6个月各指标进行观测 ,并与未行冠状动脉介入治疗的心肌梗死组比较 ,以探讨经皮冠状动脉介入治疗对心肌梗死患者左室重构的影响。方法 :将 2 7例接受经皮冠状动脉介入治疗的心肌梗死患者作为研究组 ,另取 2 9例未行经皮冠状动脉介入治疗的心肌梗死患者作为对照组 ;经皮冠状动脉介入治疗组分别于术前、术后 6个月完成各指标的测量 ,与对照组的二维超声各指标进行分析 ,以评估经皮冠状动脉介入治疗对左室重构的影响。结果 :两组心肌梗死患者术前二维超声心动图各指标无显著差异 ,经皮冠状动脉介入治疗组术后 6个月与对照组比较左室射血分数 ,短轴缩短率有不同程度改善 ,但尚无统计学意义 ,缩末容量、舒末容量较对照组显著降低 (P<0 .0 5 )。结论 :经皮冠状动脉介入治疗术可改善缺血 ,延缓心肌梗死后的心室重构 ,促进顿抑及冬眠心肌的恢复

Observation of percutaneous coronary intervention on left ventricular remodeling of myocardial infarction

Objective To observe the indexes changes in patients with myocardial infarction before and six months after percutaneous coronary intervention(PCI) with 2-dimensional echocardiography(2 DE) and to explore the impact of PCI on left ventricular remodeling generated as a result of myocardial infarction.Methods Twenty-seven patients who received PCI were enrolled in this study as PCI group and twenty-nine patients who did not receive PCI as control group.The measurements of indexes were respectively completed before PCI and six months after PCI in PCI group,the corresponding indexes were also completed in control group at same time.By comparing the 2 DE indexes before PCI and six months after PCI between two groups,the impact of PCI on left ventricular remodeling was assessed.Results There was no significant difference in 2 DE indexes between two groups before PCI.LVEF and FS were improved six months after PCI but no significant difference was found;however end-diastolic diameter and end-systolic diameter were significantly lower in PCI group than those in control group (P<0.05).Conclusion Successful patency restoration of infarct-related arteries by PCI can improve systolic/diastolic dysfunction,terminate or slow remodeling and promote recovering of hibernating myocardium.