清热养阴汤治疗鼻咽癌放疗后急性口咽黏膜反应的临床观察

目的：观察清热养阴汤治疗鼻咽癌放疗的急性口咽黏膜反应的临床疗效。方法：按随机数字表法将84例鼻咽癌患者分为两组：治疗组44例,放疗第1天同时口服清热养阴汤;对照组40例,放疗第1天开始口服维生素B12片。动态观察治疗前后临床疗效及免疫指标。结果：治疗组有效率84.1%,对照组有效率67.5%。两组有效率比较差异有显著统计学意义（P〈0.05）。结论：清热养阴汤改善鼻咽癌患者的免疫功能及防治放疗后口咽黏膜反应效果较好。

Clinical Observation on Qingre Yangyin Decoction in the Treatment of Acute Oropharyngeal Mucosa Reaction after Radiotherapy of Nasopharyngeal Carcinoma

Objective：To observe the clinical efficacy of Qingre Yangyin Decoction in the treatment of acute oropharyngeal mucosa reaction after radiotherapy of nasopharyngeal carcinoma（NPC）.Methods：84 cases NPC patients were divided into two groups with the method of random number table.44 cases in the treatment group were also given self formulated Qingre Yangyin Decoction on the first day of radiotherapy;40 cases in the control group were given vitamin B12 tablets on the first day of radiotherapy.Clinical efficacy and immune parameters were observed dynamically before and after treatment.Results：The efficiency of the treatment group was 84.1% while the control group was 67.5%.Efficiency difference between the two groups was statistically significant（P0.05）.Conclusion：Qingre Yangyin Decoction can achieve better efficacy in improving immune function of patients with nasopharyngeal carcinoma,preventing and treating oropharyngeal mucosa reaction after radiotherapy.