急诊尿激酶静脉溶栓治疗急性心肌梗塞76例临床研究

目的:研究急诊静脉溶栓治疗急性心肌梗塞(AMI)的疗效。方法:对76例急诊尿激酶静脉溶栓治疗的AMI病例进行回顾性分析。并以发病至溶栓时间的6h为界分组,比较两组病例的疗效。结果:本组冠脉再通率73.7%;轻度出血发生率11.8%,病死率15.8%,主要死因:心脏泵衰竭和严重心律失常。<6h组的冠脉再通率、轻度出血发生率、病死率分别是:84.0%、10.0%、8.0%;6～12h组分别是53.8%、15.4%、30.8%;两组冠脉再通率、病死率对比有显著性差异(P分别<0.01,<0.05);轻度出血发生率对比无显著性差异。结论:急诊静脉溶栓治疗急性心肌梗塞可以显著提高AMI的救治疗效,值得在基层医院推广。

Study of intravenous injection urokinase during emergency treatment in 76 patients with acute myocardium infarciton

Objective:To study the effect of intravenous injection urokinase during emergency treatment in 76 patients with acute myocardium infarction(AMI).Methods:Retrospectively analyzed the data of 76 AMI patients treated with intravenous injection urokinase emergency.The 76 patients were divided two groups according time of onset to thrombolysis:<6 h group and 6~12 h group.The effects of two groups were compared.Results:The recanalization rate of coronary artery was 73.3%,the hyporrea rate was 11.8% and mortality was 15.8% in whole group(76 cases).Compared with 6~12 h group,the recanalization rate increased(84.0%,P<0.01)and the mortality decreased(8.0%,P<0.05)in <6 h group,but the hyporrea rate was no difference(P>0.05)between two groups.Conclusion:Intravenous injection urokinase during emergency treatment may increase therapeutic effect for AMI patients;it may be generalized in substrate hospital.