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青年缺血性脑卒中抗心磷脂抗体的检测
引用本文:崔若玫,吕昭萍,李喜枝.青年缺血性脑卒中抗心磷脂抗体的检测[J].实用全科医学,2010,8(4):432-432,461.
作者姓名:崔若玫  吕昭萍  李喜枝
作者单位:云南省昆明医学院第一附属医院风湿免疫科,650032 
摘    要:目的探讨青年人缺血性脑卒中与抗心磷脂抗体(ACA)的关系及对预后的影响。方法测定青年人脑卒中组73例和健康体检者(对照组)30例患者血清ACA的阳性率,计算其异常率并进行比较。按脑卒中患者临床神经功能缺损程度评分(CNFDS)标准对患者进行评分。结果病例组ACA阳性率高于对照组(P〈0.001); 病例组中,ACA阳性者中多灶脑梗死率高于ACA阴性者(P=0.016); ACA阳性者中再发脑卒中高于ACA阴性者(P=0.040); 病例组中ACA阳性者患者CNFDS评分较高,中位数为18(6~35),且预后不良。结论ACA可作为临床评价脑梗死严重程度和预后的生物学指标。

关 键 词:脑梗死  青年人  抗心磷脂抗体  预后

Detection of Anticardiolipin Antibodies in Young Patients with Ischemic Stroke
CUI Ruo-mei,LV Zhao-ping,LI Xi-zhi.Detection of Anticardiolipin Antibodies in Young Patients with Ischemic Stroke[J].Applied Journal Of General Practice,2010,8(4):432-432,461.
Authors:CUI Ruo-mei  LV Zhao-ping  LI Xi-zhi
Institution:CUI Ruo-mei,LV Zhao-ping,LI Xi-zhi.Department of Rheumatology , Immunology,the First Affiliated Hospital of Kunming Medical College,Kunming 650032,Yunnan,China
Abstract:Objective To explore the relationship between anticardiolipin antibodies(ACA) and ischemic stroke and its effect on the prognosis of brain infarction.Methods 73 young thrombosis patients and 30 healthy individuals as control were enrolled in the study.The serum level and abnormal rate of ACA were determined.All the patients were scored by clinic neurological function deficit scale(CNFDS).Results The rate of ACA in the thrombosis patients was higher than that in controls(P<0.001).The ACA positive rate in pat...
Keywords:Cerebral stroke  Young people  Anticardiolipin antibodies  Prognosis  
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