| 类风湿关节炎表皮生长因子及β_2微球蛋白的测定 |
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| 引用本文： | 林星,郑斌生,林玲,杨萍,陈平,陈健. 类风湿关节炎表皮生长因子及β_2微球蛋白的测定[J]. 现代诊断与治疗, 2004, 15(6): 327-328 |
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| 作者姓名： | 林星 郑斌生 林玲 杨萍 陈平 陈健 |
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| 作者单位： | 福建医科大学福清教学医院,福建,福清,350300 |
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| 基金项目： | 福建省福清市科技发展基金资助 |
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| 摘 要： | 目的 探讨表皮生长因子 (EGF)与 β2 微球蛋白 ( β2 M )在类风湿关节炎 (RA)发病机理及诊断中的意义。方法 用放射免疫分析法 (RIA)测定 71例RA患者血清EGF、β2 M。结果 RA患者血清EGF、β2 M显著升高 ,说明EGF、β2 M在RA的发病中可能起一定作用 ,但与RA的活动性无关。
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| 关 键 词： | 表皮生长因子 β2微球蛋白 类风湿关节炎 |
| 文章编号： | 1001-8174(2004)06-0327-02 |
| 修稿时间： | 2004-08-26 |
Determine of Epidermal Growth Factor and β2-Microglobulin in Patients with Rheumatoid Arthritis |
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| LIN Xing,ZHENG Bin-sheng,LIN Ling,YANG Ping,CHEN Ping,CHEN Jian. Determine of Epidermal Growth Factor and β2-Microglobulin in Patients with Rheumatoid Arthritis[J]. Modern Diagnosis & Treatment, 2004, 15(6): 327-328 |
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| Authors: | LIN Xing ZHENG Bin-sheng LIN Ling YANG Ping CHEN Ping CHEN Jian |
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| Abstract: | Objective To investigate the roles of epidermal growth factor(EGF) and β_2-microglobulin(β_2-M) in the pathogenesis and diagnosis of rheumatoid arthritis(RA).Method 71 patients with RA were observed.EGF and β_2-M in serum were measured by radioimmunoassay.Results The levels of EGF and β_2-M in serum of patients with RA were significantly higher than those of the controls.Conclusions EGF and β_2-M may play a role in the pathogenesis of RA,but they aren't related to the activity of RA. |
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| Keywords: | Epidermal growth factor(EGF) β_2-microglobulin(β_2-M) Rheumatoid arthritis |
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