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| 升压疗法在大动脉狭窄所致内分水岭脑梗死的临床研究 | |
| 引用本文： | 姜玉龙,崔翔宇,李志强,姜建东,庄爱霞,沈霞.升压疗法在大动脉狭窄所致内分水岭脑梗死的临床研究[J].中西医结合心脑血管病杂志,2012,10(3):293-295. |
| 作者姓名： | 姜玉龙 崔翔宇 李志强 姜建东 庄爱霞 沈霞 |
| 作者单位： | 1. 徐州医学院、连云港市第二人民医院,222000 2. 山东省德州市人民医院 3. 山西省汾阳医院 4. 江苏省连云港市第二人民医院 5. 徐州医学院,222000 |
| 摘 要： | 目的对颅内外大动脉狭窄致内分水岭脑梗死患者进行扩容治疗,提高患者平均动脉压,观察对血流动力学的影响。方法入选43例大动脉狭窄所致内分水岭脑梗死患者,应用药物升高平均动脉血压,按升高平均动脉压幅度的不同,设立两组,A组:平均动脉压升高10%～15%;B组:平均动脉压升高15%以上。行MRA检查观察大血管狭窄状况,按狭窄责任大血管部位的不同,设立颈内动脉狭窄组及大脑中动脉狭窄组两个亚组。通过TCD检测两组患者治疗前后责任侧大脑中动脉血流速度改变,评估患者升压治疗前后血压变化与血流动力学之间的关系。结果 B组患者患侧大脑中动脉TCD测定脑血流速上升值较A组有统计学意义(P<0.05)。结论扩容升压治疗可以明显改善分水岭脑梗死的血流动力学指标,从而改善患者预后。 |
| 关 键 词： | 颈内动脉狭窄 大脑中动脉狭窄 内分水岭脑梗死 平均动脉压 血流动力学 |
Clinical Observation on Elevating Blood Pressure in Treatment of Internal Watershed Infarction Due to Large Cerebral Artery Stenosis |
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| Institution: | Jiang Yulong,Cui Xiangyu,Li Zhiqiang,et al // Xuzhou Medical College(Xuzhou 222000) |
| Abstract: | Objective To investigate the effect of elevating mean artery blood pressure on hemodynamics of patients(pts) with internal watershed infarction due to extra-and intra-large cerebral artery stenosis.Methods Forty-three pts with internal watershed infarction were divided into group A(increaseing blood pressure 10% to 15%) and group B(increaseing blood pressure more than 15%).Blood velocity in ipsilateral middle cerebral artery was detected by transcranial Doppler pre-and post-treatment.Results There was significantly difference in blood velocity of ipsilateral middle cerebral artery between group B and group A(P<0.05).Conclusion Blood pressure increase may improve the hemodynamics of internal watershed infarction and improve the prognosis of internal watershed infarction,especially for pts with stroke resulted from internal carotid arteriosclerosis. |
| Keywords: | carotid artery stenosis middle cerebral artery stenosis internal watershed infarction mean artery blood pressure hemodynamics |
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