| 酒依赖者戒饮期认知功能及其相关因素研究 |
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| 引用本文： | 李艳祥,王学义,姚绍敏,王相红,王岚. 酒依赖者戒饮期认知功能及其相关因素研究[J]. 中国药物依赖性杂志, 2010, 19(2): 100-104 |
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| 作者姓名： | 李艳祥 王学义 姚绍敏 王相红 王岚 |
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| 作者单位： | 河北医科大学第一医院精神卫生研究所,河北省认知与脑老化神经科学重点实验室,石家庄,050031 |
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| 摘 要： | 目的:研究酒依赖者戒饮期的认知功能、脑电图、脑CT、酒依赖程度和共病的相关因素。方法:32例酒依赖组:确定酒依赖的程度,进行脑电图及头颅CT检查,入组3-4周内进行认知功能检测。酒依赖组分首发组及复饮组,比较两组患者认知功能、头颅CT、脑电图、依赖程度及共病情况。28例健康对照组只做认知功能检查。结果:酒依赖组的言语记忆(t=-2.95,P<0.01)、视觉记忆(t=-4.04,P<0.01)、数字序列测验(t=-2.68,P<0.01)的测验成绩明显低于对照组;执行功能的威斯康星卡片分类测验(WCST)各项测试得分、伦敦塔测验(t=-2.39,P<0.05)及Stroop色词测验(t=-4.80,P<0.01)得分也明显低于对照组。复饮组较首发组的认知功能损害程度严重,且头颅CT及脑电图的异常率较首发组高;脑电图异常及脑CT异常与复饮呈正相关。结论:酒依赖患者戒饮期的认知功能损害仍持续存在,反复饮酒者的认知功能损害程度及头颅CT及脑电图异常高于首发者。
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| 关 键 词： | 酒依赖 认知功能 脑CT 脑电图 |
STUDY ON THE COGNITIVE FUNCTION AND OTHER FACTORS IN ALCOHOLICS AT WITHDRAWAL PERIOD |
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| LI Yanxiang,WANG Xueyi,YAO Shaomin,WANG Xianghong,WANG Lan. STUDY ON THE COGNITIVE FUNCTION AND OTHER FACTORS IN ALCOHOLICS AT WITHDRAWAL PERIOD[J]. Chinese Journal of Drug Dependence, 2010, 19(2): 100-104 |
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| Authors: | LI Yanxiang WANG Xueyi YAO Shaomin WANG Xianghong WANG Lan |
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| Affiliation: | LI Yanxiang,WANG Xueyi,YAO Shaomin,WANG Xianghong,WANG Lan(Mental Health Institute,the First Hospital of Hebei Medical University,Shijiazhuang,050031) |
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| Abstract: | Objective:To investigate the cognitive function of alcoholics at withdrawal period,their brain CT,electroencephalogram,degree of alcohol dependence and comorbidity of other mental diseases.Methods:Thirty two inpatients were divided into two groups,based on their hospitalization times:first hospitalized patients for alcoholism and the relapsed patients,both of whom were tested for alcohol dependence,undertook brain CT,electroencephalogram when they were recruited in hospital.All the patients were measured wi... |
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| Keywords: | alcohol dependence cognitive function brain CT electroencephalogram |
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