北京同步辐射装置(BSRF)医学成像实验研究

目的 探讨同步辐射技术用于医学成像的应用价值。方法 利用同步辐射光源的空间相干性、准直性、高亮度等特性进行成像实验。在北京同步辐射装置（BSRF）的4W1A束线上，使用衍射增强技术（DEI）对肝、肾等组织进行成像，部分结果与病理结果进行对照；使用白光技术对大鼠冠状动脉进行成像。2种技术的分辨率通过显微放大法获得。结果 成像结果均具有较高的衬度和分辨率，显微放大法获得的分辨率为微米量级。通过白光技术获得的大鼠心脏冠状动脉图像可显示到二级分支结构，部分可达三级结构。结论 DEI和白光技术等同步辐射成像技术可显示弱吸收组织及血管等微细结构，具有较好的应用前景。

An experimental study on medical imaging at the Beijing Synchrotron Radiation Facility (BSRF)

Objective To investigate the clinical potential of synchrotron radiation(SR)on medi- cal imaging.Methods Experiment study was performed for generation of imaging through the SR light source's spatial coherence,collimation,and brightness.With the 4W1A beam at Beijing SR Facility (BSRF),the diffraction enhanced imaging(DEI)was applied to image sample tissues of liver and kidney. Results were compared with pathological findings.The white light was used to image mouse coronary artery. The resolution was calculated by the micro-magnify method.Results All images obtained had good quali- ties with high resolution and contrast.The micron grade resolution was verified by the micro-magnify meth- od.The second branch of vessel structure could be identified in mouse coronary artery,and the third branch of vessel structure was also identified to certain extent.Conclusion The SR imaging technique including DEI and white light can be used for the identification of weak absorption tissue and minuteness of structure including blood vessels.