颞叶躯体感觉中枢功能磁共振研究

目的利用血氧水平依赖功能磁共振成像观察正常人在躯体感觉刺激时中枢的兴奋情况。方法研究包括30名正常志愿者。功能成像采用组块设计。在任务刺激中通过专用电刺激仪刺激手部皮肤,刺激持续时间1000ms、间隔1000ms。用SPM99专业图像处理软件处理所得图像。结果体感刺激明显激活位于两侧中央前、后回的第一、第二躯体感觉皮层和颞上回。额叶、缘上回和小脑亦可见散在激活区。刺激手对侧半球激活强度比同侧大。双手刺激的激活无显著性差异。结论体感刺激激活两侧第一、第二躯体感觉皮层。颞叶和其他脑功能区参与处理体感刺激。

Somatic Sensory Centre of Temporal Lobe:fMRI Study

Objective To observe responses of brain evoked by somatic stimuli in healthy subjects with blood oxygenation level-dependent functional magnetic resonance imaging.Methods There were 30 healthy subjects in the study. Block design was used infunctional MR imaging. In experimental tasks somatic stimuli was executed to the hands of every subject at duration 1000 ms,interstimulus intervals 1000 ms.The professional software-SPM99 was performed to process the images.Results For healthy subjects to somatic stimuli, significant activation was observed in bilateral primary and secondary somatic cortex of precentral gyri and postcentral gyri, and temporallobes. Scattered activations could be seen in frontal lobes, supramarginal gyri and hemisphere of cerebella. There was more intensiveactivation in right hemisphere than that in left. There was no significant difference between the activation evoked by somatic stimuli of leftand right extremities. Conclusion somatic stimuli can evoke significant activations in bilateral primary and secondary somatic cortex.Temporal lobes and other brain areas join in the process of somatic stimuli.