Histological observations of hard tissue barrier formation in amputated dental pulp capped with α-tricalcium phosphate containing calcium hydroxide |
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| Authors: | K. Yoshiba N. Yoshiba M. Iwaku |
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| Affiliation: | Department of Operative Dentistry and Endodontics, Niigata University School of Dentistry, Japan |
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| Abstract: | Abstract This study was performed to evaluate the pulpal response to α-tricalcium phosphate (αTCP) containing calcium hydroxide (Ca(OH)2). The dental pulps of monkeys were amputated and dressed with four agents: αTCP, αTCP containing 1% Ca(OH)2, αTCP containing 5% Ca(OH)2, and Ca(OH)2 being used as a control. The pulpal responses were histologically evaluated after 4 and 8 weeks. The pulp tissue treated with αTCP proliferated above the level of the original wound surface, and a thin layer of hard tissue barrier was formed directly against the capping agent. The barrier demonstrated atubular matrix lined with flattened or cuboidal cells, but occasionally appeared irregular in form. Ca(OH)2 dressing resulted in destruction of pulp tissue, with a thick hard tissue barrier being formed below the level of the exposure site. The barrier consisted coronally of osteodentin and pulpally of tubular dentin lined with odontoblast-like cells. By contrast, 1% Ca(OH)2 added to αTCP produced a slight proliferation of pulp tissue. An atubular matrix barrier, pulpally lined with cuboidal cells, formed above the exposure site. It was later followed by the formation of tubular matrix lined with columnar cells. Teeth treated with 5% Ca(OH)2, showed a thin necrotic layer and a thick barrier formation. The barrier was composed of tubular dentin-like tissue lined with odontoblast-like cells. It would appear that αTCP containing a small amount of Ca(OH)2 may be clinically useful as a capping agent, as it induced consistent hard tissue formation, without excessive destruction of underlying pulp tissue. |
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| Keywords: | pulpotomy pulp capping α-tricalcium phosphate: calcium hydroxide |
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