| 肺癌患者血浆纤维蛋白原、D-二聚体水平与预后的相关性研究 |
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| 引用本文： | 姜正华,桑慧颖,朱慕云,朱湘平,葛辉,丁平.肺癌患者血浆纤维蛋白原、D-二聚体水平与预后的相关性研究[J].实用诊断与治疗杂志,2009,23(5). |
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| 作者姓名： | 姜正华 桑慧颖 朱慕云 朱湘平 葛辉 丁平 |
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| 作者单位： | 扬州大学临床医学院江苏省苏北人民医院呼吸内科,江苏省扬州市,225001 |
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| 摘 要： | 目的:探讨肺癌患者血浆纤维蛋白原、D-二聚体水平与预后的相关性。方法:测定60例肺癌患者(肺癌组)及20例健康体检者(对照组)血浆纤维蛋白原、D-二聚体水平并进行对比分析。结果:肺癌组血浆纤维蛋白原、D-二聚体水平高于对照组(P<0.05),肺癌组血浆纤维蛋白原、D-二聚体水平与病理类型、肿瘤大小、TNM分期之间无明显关系。肺癌患者血浆纤维蛋白原、D-二聚体水平与生存期呈显著负相关。结论:肺癌患者血液处于高凝状态,血浆纤维蛋白原、D-二聚体水平与患者的预后密切相关。抗凝治疗对控制肺癌患者病情的发展及预后可能有重要的临床意义。
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| 关 键 词： | 肺癌 纤维蛋白原 D-二聚体 预后 |
Correlative study on plasma levels of fibrinogen, D-dimer and prognosis in patients with lung cancer |
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| JIANG Zhenghua,SANG Huiying,ZHU Muyun,et al..Correlative study on plasma levels of fibrinogen, D-dimer and prognosis in patients with lung cancer[J].Journal of Practical Diagnosis and Therapy,2009,23(5). |
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| Authors: | JIANG Zhenghua SANG Huiying ZHU Muyun |
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| Institution: | JIANG Zhenghua,SANG Huiying,ZHU Muyun,et al.Department of Respiratory Medicine,Subei Hospital,Yangzhou 225001,China |
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| Abstract: | Objective To explore the relationship between plasma levels of fibrinogen and D-dimer,and the prognosis in patients with lung cancer.Methods The plasma levels of fibrinogen and D-dimer were detected in 60 patients with lung cancer and 20 normal controls.Results The D-dimer and plasma fibrinogen were significantly higher than those of normal controls(P<0.05).The plasma levels of fibrinogen and D-dimer in patients with lung cancer were not related to histological classification,the size of the primary tumors ... |
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| Keywords: | Lung cancer fibrinogen D-dimer prognosis |
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