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Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade
Authors:Lixia Du  Xueming Hu  Wei Yang  Hanikezi Yasheng  Shenbin Liu  Wenwen Zhang  Yang Zhou  Wenqiang Cui  Jianyu Zhu  Zheng Qiao  Qiliang Maoying  Yuxia Chu  Hong Zhou  Yanqing Wang  Wenli Mi
Affiliation:1. Department of Integrative Medicine and Neurobiology, Institutes of Integrative Medicine, School of Basic Medical Sciences, Institutes of Brain Science, Brain Science Collaborative Innovation Center, State Key Laboratory of Medical Neurobiology, Fudan University, Shanghai, People's Republic of China;2. Department of Immunology, Nanjing Medical University, Nanjing, People's Republic of China
Abstract:
Keywords:astrocytes  chronic itch  IL-33  ST2  STAT3
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