| 葛根素注射液治疗突发性耳聋的Meta分析 |
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| 引用本文： | 李勉珊,王杰松,李保卫,刘刚. 葛根素注射液治疗突发性耳聋的Meta分析[J]. 中国药房, 2006, 17(1): 44-46 |
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| 作者姓名： | 李勉珊 王杰松 李保卫 刘刚 |
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| 作者单位： | 解放军第306医院,北京市,100101 |
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| 摘 要： | 目的利用Meta分析方法对葛根素注射液治疗突发性耳聋的临床试验进行分析,评价其治疗效果。方法检索1994年~2004年国内发表的葛根素注射液治疗突发性耳聋临床试验的相关文献,采用Review Manager4.2软件对符合条件的文献进行荟萃分析。结果共有4个临床试验纳入本次研究,同质性检验X2=0.80,P>0.05,故采用固定效应模型进行分析。与对照组比较,葛根素注射液治疗突发性耳聋总有效率更高,比值比为2.05,95%可信区间为1.10~3.82(P<0.05)。结论临床可选用葛根素注射液治疗突发性耳聋。
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| 关 键 词： | 葛根素注射液 突发性耳聋 Meta分析 |
| 文章编号： | 1001-0408(2006)01-0044-03 |
| 收稿时间： | 2005-09-01 |
| 修稿时间： | 2005-10-18 |
Meta-analysis of Kakkonein Injection in the Treatment of Sudden Hearing Loss |
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| LI Mianshan,WANG Jiesong,LI Baowei,LIU Gang. Meta-analysis of Kakkonein Injection in the Treatment of Sudden Hearing Loss[J]. China Pharmacy, 2006, 17(1): 44-46 |
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| Authors: | LI Mianshan WANG Jiesong LI Baowei LIU Gang |
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| Affiliation: | No. 306 Hospital of PLA, Beijing 100101, China |
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| Abstract: | OBJECTIVE:To conduct a meta-analysis on the clinical trails of kakkonein injection for sudden hearing loss and to evaluate its outcome.METHODS:The related literature concerning the clinical trials of kakkonein injection in treating sudden hearing loss published domestically between1994and2004were retrieved.Meta analysis on the selected literature was conducted by means of Review Manager4.2software.RESULTS:A total of4clinical trials were included in our study,in ho-mogeneity test X 2 =0.80,P>0.05,thus a fixed effect model was applied.As compared with the control group,kakkonein in-jection has a higher total effective rate with the odds ratio at2.05and95%confidence interval at1.10～3.82(P<0.05).CO_ NCLUSION:Kakkonein injection can be used as an option in the clinical treatment of sudden hearing loss. |
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| Keywords: | Kakkonein injection Sudden hearing loss Meta analysis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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