温经汤对月经病实寒证患者血清卵泡刺激素、促黄体生成素、雌二醇、黄体酮、睾酮的影响

目的探讨温经汤对月经病实寒证患者血清卵泡刺激素(FSH)、促黄体生成素(LH)、雌二醇(E2)、黄体酮(P)、睾酮(T)的影响。方法选取90例月经病实寒证患者。按照随机数表法分为观察组和对照组。对照组采用常规治疗,观察组采用温经汤治疗,观察2组患者疗效,比较血清FSH、LH、E_2、P、T、5-羟色胺(5-HT)、β-内啡肽(β-EP)、子宫血流动力学指标变化。结果治疗后,观察组总有效率显著高于对照组(P0.05);观察组FSH、LH、E_2显著高于对照组(P0.05),5-HT显著低于对照组,β-EP显著高于对照组(P0.05);观察组PSV显著大于对照组,RI、PI显著小于对照组(P0.05)。结论温经汤治疗月经病实寒证疗效显著,能够改善血清FSH、LH、E_2、P、T水平,可调节患者的内分泌紊乱。

Effect of wenjing decoction on serum follicle stimulating hormone,luteinizing hormone,estradiol, progesterone and testosterone of patients with menopathy of excess-cold syndrome

Objective To explore effect of wenjing decoction on serum follicle-stimulating hormone (FSH),luteinizing hormone (LH),estradiol (E2),progesterone Prog (P),testosterone (T) of patients with menopathy of excess-cold syndrome.Methods Totally 90 patients with menopathy of excess-cold syndrome were selected and randomly divided into observation group (n =45) and control group (n =45).The control group was treated with routine treatment,while the observation group was treated with wenjing decoction.The therapeutic effect,serum FSH,LH,E2,P,T,5-HT,β-EP,uterine hemodynamics of two groups after treatment were compared.Results After treatment,the total effective rate of the observation group was significantly higher than the control group (P ＜0.05).The FSH,LH,E2 level in the observation group were significantly higher than the control group (P ＜ 0.05),5-HT was significantly lower than the control group,and β-EP was significantly higher than the control group (P ＜ 0.05).PSV in the observation group was significantly higher than the control group,while RI and PI were significantly lower than the control group (P ＜ 0.05).Conclusion Wenjing decoction is effective in treatment of patients with menopathy of excess-cold syndrome,which can improve serum FSH,LH,E2,P,T levels and regulate the endocrine disorder.