普外科围手术期抗生素应用的探讨

目的 探讨普外科围手术期如何更合理地应用抗生素。方法 121例病例均在1998年11月－2000年6月入院，分深静脉、胆汁培养、引流管三组。所应用抗生素为先锋六号、西力欣、先锋铋、罗氏芬、泰能、环丙沙星和灭滴灵等。记录使用时间、剂量，同时作伤口分泌物、血、引流物培养和药敏试验。结果 外科使用抗生素指征过宽、时间过长，导致临床上耐药菌种增加，甚至是多种药物耐药。结论 临床上要合理应用抗生素。

The application of antibiotics in the peri-operative period of the general surgery

Objective To explore reasonable application of antibiotics in the peri-operative period of the general surgery.Methods 121 cases who were admitted from Nov. 1998 to Jun. 2000 were divided into three groups including deep-vein group, biliary culture group and drainage-rube group. The antibiotics were Cefradine, Cefuroxime, Cefoperazone, Ceftriaxone, Imipenem, Ciprofloxacin and Metronidazole. We recorded the dosages and applying-time of the antibiotics. We also carried out the culture of the blood, cut-secreta and drainage tube at the same time.Results The clinical doctors applied the antibiotics with excess of indications and applying-time. That brought about more and more drug-fast bacteria, even multiple drug-fast bacteria.Conclusion We must apply the antibiotics reasonable in the peri-operation.