液基细胞学联合阴道镜在宫颈病变诊治中的临床应用

目的 探讨液基细胞学联合阴道镜对宫颈病变诊断的应用价值.方法 对门诊174例细胞学异常TBS诊断≥未明确诊断意义的非典型鳞状细胞(ASC-US)]的患者,进行阴道镜检查及活检,对其临床资料进行回顾性分析,比较细胞学诊断及阴道镜活检病理结果的符合率.结果 细胞学异常174例中,非典型鳞状细胞(ASC)占27.0%(47/174),低度鳞状上皮内痛变(ISIL)占52.9%(92/174)、高度鳞状上皮内病变(HSIL)占19.0%(33/174)、鳞状细胞癌(SCC)占1.1%(2/174).阴道镜活检组织病理学诊断宫颈良性细胞改变(BCC)占16.1%(28/174),宫颈上皮内瘤变(CIN)I级占42.0%(73/174),CIN Ⅱ级18.4%(32/174),CIN Ⅲ级21.8%(38/174),SCC1.7%(3/174).细胞学的阳性符合率为83.9%(146/174).结论 液基细胞学结合阴道镜检查及活检能够显著提高宫颈病变的检出率及诊断的正确率,为患者及时正确的治疗提供科学的依据,二者结合应用将更有利于科学的管理宫颈病变.

Clinical value of thinprep cytology test combined with colposcopy in diagnosis of cervical lesion

Objective To investigate the clinical value of thinprep cytology test(TCT) combined with colposcopy in diagnosis of cervical lesion. Methods Retrospective analysis was conducted in 174 females with abnormal cervical smear. All the patients underwent colposcopy to screen the cervical lesions. According to the pathological results,the clinical value of TCT and colposcopy was analyzed and compared. Results In the 174 cases with abnormal cervical smear,the positive rate of atypical squamous cells(ASC) was 27. 0% (47/174). There were 92 low grade squamous intraepithelial lesion (LSIL) (52. 9%) ,33 high grade squamous intraepithelial lesion (HSIL) (19. 0%) and 2 squamous cell cancinoma (SCC) (1. 1%) . According to the diagnosis by biopsy and pathology,the positive rate of benign cervical cell(BCC) was 16. 1% (28/174) .cervical intraepithelial neoplnsia (CIN) I 42. 0% (73/174), CIN II 18.4% (32/174), CIN ffl 21. 8% (38/174) and SCC 1. 7% (3/174) . The coincidence rate of TCT and pathology was 83. 9% (146/174). Conclusions TCT and colposcopy are a practical approach for detecting cervical lesion. TCT combined with colposcopy is the optimal screening approach for cervical lesion, which can enhance the sensitivity and specificity of the diagnosis of cervical lesions.