| 前列腺特异抗原和雌激素、孕激素受体在乳腺癌中的表达及其相关性 |
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| 引用本文： | 杨幼萍,周涛,叶民.前列腺特异抗原和雌激素、孕激素受体在乳腺癌中的表达及其相关性[J].中国癌症杂志,2000,10(4):333-335. |
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| 作者姓名： | 杨幼萍 周涛 叶民 |
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| 作者单位： | 1. 温岭市第一人民医院病理科,浙江温岭,317500
2. 台州医院病理科,浙江台州,317000 |
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| 摘 要： | 目的：研究前列腺特异抗原在乳腺癌组织中的表达及其与ＥＲ、ＰＲ表达的关系。方法：采用免疫组化法同１０２例乳腺癌的抗人体前列腺特异抗原（ＰＳＡ），雌激素受体（ＥＲ）和孕激素受体（ＰＲ）。结果：２６例ＰＳＡ阳性（２５．５％），ＰＳＡ＾＋和ＥＲ＾＋、ＰＲ之间存在密切关系（Ｐ〈０．０５）。ＰＳＡ＾＋、ＥＲ＾＋的乳腺癌液下淋巴结转移率明显低于ＰＳＡ＾－、ＥＲ＾－的乳腺癌（Ｐ〈０．０５）。结论：ＰＳＡ、ＥＲ、Ｐ
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| 关 键 词： | 乳腺癌 前列腺特异抗原 雌激素受体 孕激素受体 |
| 文章编号： | 1007-3639(2000)04-0333-03 |
| 修稿时间： | 1999年8月17日 |
Experssion of prostatic specific antigen,estrogen and progesterone receptors in human breast cancer and their correlation |
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| YANG You ping,ZHOU Tao,YE Ming.Experssion of prostatic specific antigen,estrogen and progesterone receptors in human breast cancer and their correlation[J].China Oncology,2000,10(4):333-335. |
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| Authors: | YANG You ping ZHOU Tao YE Ming |
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| Abstract: | Purpose:To investigate the expression of prostatic specific antigen(PSA), estrogen receptor (ER) and progesterone receptor (PR) in human breast cancer and their correlation. Methods:Immunohistochemistry was performed in 102 paraffin embedded breast cancer cases to analyze PSA,ER and PR immunophenotype by using the standard LSAB technique.Results:26 cases of breast cancer expressed the PSA antigen, and a significant correlation of PSA expression with ER and PR was also found (P<0 05).Conclusions:PSA expression correlates significantly with tumor size,biological behavior, ER condition and lymph node metastasis In patients with breast cancer, the expression of PSA is associated with a better prognosis. |
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| Keywords: | breast tumor breast cancer prostatic specific antigen estrogen receptor progesterone receptor immunohistochemistry |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
