MIGRAINE, TYRAMINE AND BLOOD SEROTONIN |
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Authors: | Dewey K. Ziegler MD Ruth Stephenson Hassanein MSPH Daniel F. Ward MD PhD |
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Affiliation: | From the Department of Neurology, University of Kansas Medical School, Kansas City, Kansas 66103 and;the Department of Biometry, University of Kansas Medical School, Kansas City, Kansas 66103. |
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Abstract: | SYNOPSIS Whole blood serotonin levels and headache symptoms were studied in 26 migrainous patients during a three day period with administration of tyramine the first day, reserpine the second day. No significant changes in serotonin occurred after tyramine; headache severity was not associated with change in blood serotonin, which dropped to low levels after a small dose of reserpine without precipitating migraine in most patients. |
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