Complex karyotype in a low grade phyllodes tumor of the breast |
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| Authors: | Ladesich James Damjanov Ivan Persons Diane Jewell William Arthur Teresa Rogana Jennifer Davoren Barbara |
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| Affiliation: | Department of Surgical Pathology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. jladesich@kumc.edu |
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| Abstract: | Cytogenetic analysis of a phyllodes tumor of low grade malignancy disclosed the karyotype 52-55,XX, -1,+5,+7,+9,+10,+11,-15,+18,-19,+20,der(21)t(1;21)(p13;q22),+mar1x 2-4,+mar2[cp18]/46,XX. This study shows that a complex chromosome karyotype can be found in low-grade phyllodes tumors and is not necessarily a sign of extreme malignancy of these neoplasms. |
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