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炎痛消软膏抗炎镇痛作用的实验研究
引用本文:朱波,朱丽,赵怡然,杜智敏.炎痛消软膏抗炎镇痛作用的实验研究[J].哈尔滨医科大学学报,2002,36(4):290-292.
作者姓名:朱波  朱丽  赵怡然  杜智敏
作者单位:1. 哈尔滨医科大学药学院,黑龙江哈尔滨,150086
2. 齐齐哈尔医学院第一附属医院,黑龙江齐齐哈尔,161000
3. 哈尔滨医科大学第二临床医学院,黑龙江哈尔滨,150086
摘    要:目的 观察炎痛消软膏的抗炎镇痛作用。方法 采用家兔血清致大鼠皮肤水肿法和组织胺致大鼠皮内色素渗出法研究炎痛消软膏的抗炎作用;热板法研究炎痛消软膏的镇痛作用。结果 实验研究表明,炎痛消软膏能显著抑制大鼠皮肤肿胀和皮下色素的渗出,延长小鼠的痛反应时间,与空白对照组比较有显著差异,与万应膏组间无显著差异,且在抗炎方面优于万应膏组。结论 炎痛消软膏具有抗炎镇痛作用。

关 键 词:炎痛消软膏  抗炎  镇痛  动物模型
文章编号:1000-1905(2002)04-0290-03
修稿时间:2001年12月31

Studies on the anti-inflammatory and analgesic action of Yantongxiao unguent
ZHU Bo,ZHU Li,ZHAO Yi-ran,et al.Studies on the anti-inflammatory and analgesic action of Yantongxiao unguent[J].Journal of Harbin Medical University,2002,36(4):290-292.
Authors:ZHU Bo  ZHU Li  ZHAO Yi-ran  
Abstract:Objective To explore the anti-inflammatory and analgesic action of Yantongxiao unguent.Methods The anti-inflammatory action of Yantongxiao unguent was observed with the method that rabbit serum caused rat skin edema and histamine caused rat skin pigment oozing ,and it's analgesic action was observed with the method of measuring mouse painful threshold by heated iron plate. Results Yantongxiao unguent could restrain the skin edema and pigment oozing from rat and raise mouse painful threshold. There was remarkable difference in comparison with blank control group, and there was no remarkable difference in comparison with Wanyinggao group. On the anti-inflammatory action, Yantongxiao unguent group was better than Wanyinggao group. Conclusion Yantongxiao unguent has anti-inflammatory and analgesic action.
Keywords:Yantongxiao unguent  anti-inflammatory  action  analgesic action  animal model  
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